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當前位置:首頁產品中心細胞相關產品細胞因子P00026Recombinant Human IL-18細胞因子

Recombinant Human IL-18細胞因子
產品簡介:

Recombinant Human Interleukin-18(Recombinant Human IL-18細胞因子) is produced by our E.coli expression system and the target gene encoding<br>Tyr37-Asp193 is expressed.

產品型號:P00026

更新時間:2025-04-24

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產品介紹

Recombinant Human IL-18細胞因子

貨號:P00026

規格:10ug/50ug/500ug/1mg

Known asInterleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor;Interleukin-1 gamma; IL-1 gamma;GIF; IL-18; IL-1g; IL1F4; MGC12320
Derived fromE.coli
PurityGreater than 95% as determined by reducing SDS-PAGE.Less than 0.1 ng/?g (1 IEU/?g).
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediay at the temperature listed below.
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 10 months
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 8X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles.
Amino Acid SequenceYFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMN PPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED
BackgroundInterleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells.

Recombinant Human Interleukin-18 is produced by our E.coli expression system and the target gene encoding
Tyr37-Asp193 is expressed.

 

Recombinant Human IL-18細胞因子訂購說明:

1、絕大部分產品備有現貨,一般情況下都能訂貨當日發貨。 
2、部分非常用產品,需提前1-2日預訂,海外期貨則需要提前3-6周預訂。 
3、部分產品價格會因貨期、批次等因素發生變化,若有變動以訂貨當日新價格為準。 
4、每日訂單截止時間為16點整,部分城市可到17點整,因超過截止時間造成當日不能發貨的將于次日安排發貨。
5、請辦理完貨款后,將底單等連同收貨人的地址、姓名、等以傳真、、短信、等形式通知我們。


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