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Anti-GADD153 Polyclonal Antibody
產(chǎn)品簡(jiǎn)介:

Anti-GADD153 Polyclonal Antibody
應(yīng)用 IHC
稀釋比例IHC 1:25-100.
交叉反應(yīng)Human

產(chǎn)品型號(hào):K106765P

更新時(shí)間:2022-08-14

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產(chǎn)品介紹

Anti-GADD153 Polyclonal Antibody

英文名稱(chēng)Anti-GADD153 Polyclonal Antibody
宿主Rabbit
別名CEBPZ;CHOP;CHOP-10;CHOP10;GADD153;C/EBPzeta;DNA damage inducible transcript 3
應(yīng)用IHC
稀釋比例IHC 1:25-100.
交叉反應(yīng)Human
蛋白分子量19kDa
Gene ID1649
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human GADD153
性狀液體
Public Immunogen RangeA synthetic peptide of human GADD153
Subcellular LocationsNucleus Cytoplasm
Swiss ProtP35638
克隆類(lèi)型Polyclonal Antibody
背景資料This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

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