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Polyclonal Antibody
K106679PAnti-CASP8 Polyclonal Antibody
產(chǎn)品型號(hào):K106679P
更新時(shí)間:2022-08-15
廠商性質(zhì):生產(chǎn)廠家
訪(fǎng) 問(wèn) 量 :936
010-50973130
產(chǎn)品分類(lèi)
Anti-CASP8 Polyclonal Antibody
英文名稱(chēng) | Anti-CASP8 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | ALPS2B;CAP4;Casp-8;FLICE;MACH;MCH5 |
應(yīng)用 | WB IHC |
稀釋比例 | WB 1:500-2000. IHC 1:50-200. |
交叉反應(yīng) | Human |
蛋白分子量 | 55kDa |
Gene ID | 841 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human CASP8 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human CASP8 |
Subcellular Locations | Cytoplasm |
Swiss Prot | Q14790 |
克隆類(lèi)型 | Polyclonal Antibody |
背景資料 | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. |
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