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Anti-CD130 Polyclonal Antibody
產(chǎn)品簡介：

Anti-CD130 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106480P

更新時(shí)間：2022-08-15

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產(chǎn)品介紹

Anti-CD130 Polyclonal Antibody

英文名稱Anti-CD130 Polyclonal Antibody
宿主Rabbit
別名CDW130;GP130;IL-6RB;IL6ST;IL-6R beta
應(yīng)用WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat
蛋白分子量65/125kDa
Gene ID3572
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human CD130
性狀液體
Public Immunogen RangeA synthetic peptide of human CD130
Subcellular LocationsCell membrane Nucleus Extracellular matrix
Swiss ProtP40189
克隆類型Polyclonal Antibody
背景資料The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.

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